Fully automated pixel-wise myocardial blood flow quantification with first-pass perfusion CMR
نویسندگان
چکیده
Methods Rest and adenosine stress perfusion imaging was performed on 17 normal volunteers. A saturation recovery SSFP dual-sequence technique was used to acquire three myocardial slices and an arterial input function (AIF) image series. A proton-density weighted image was acquired at the beginning of each series. Fully quantitative perfusion pixel maps were generated by an automated processing method, including non-rigid motion correction, surface-coil intensity correction, AIF and myocardial signal and contrast timing detection, and model constrained deconvolution. The results of the automatically generated MBF pixel maps were compared with manual quantification using an 18-segment model.
منابع مشابه
A quantitative pixel-wise measurement of myocardial blood flow by contrast-enhanced first-pass CMR perfusion imaging: microsphere validation in dogs and feasibility study in humans.
OBJECTIVES The aim of this study was to evaluate fully quantitative myocardial blood flow (MBF) at a pixel level based on contrast-enhanced first-pass cardiac magnetic resonance (CMR) imaging in dogs and in patients. BACKGROUND Microspheres can quantify MBF in subgram regions of interest, but CMR perfusion imaging may be able to quantify MBF and differentiate blood flow at a much higher resol...
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Background Quantitative first pass cardiac magnetic resonance (CMR) perfusion imaging has shown excellent interobserver agreement at a sector level in healthy volunteers and patients. In this study, we compare the myocardial blood flow (MBF) estimates in sector-wise and pixel-wise analysis. We also study the interobserver variability in pixel-wise MBF estimates from patients with coronary arter...
متن کاملA quantitative pixel-wise measurement of myocardial blood flow by contrast-enhanced first-pass CMR perfusion imaging: microsphere validation in dogs and feasibility study
A quantitative pixel-wise measurement of myocardial blood flow by contrast-enhanced first-pass CMR perfusion imaging: microsphere validation in dogs and feasibility study in humans. (2012). A quantitative pixel-wise measurement of myocardial blood flow by contrast-enhanced first-pass CMR perfusion imaging: microsphere validation in dogs and feasibility study in humans. General rights Copyright ...
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